SCHEMBL24866182

SCHEMBL24866182

COc1cc(OC2CCC2)ccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 20/20 0.81
▸ KAT7 O95251 19/20 0.81
▸ KAT6B Q8WYB5 15/20 0.81
▸ KAT8 Q9H7Z6 15/20 0.81
▸ KAT5 Q92993 14/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24866472 0.94 KAT6A (0.81) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL31372081 0.91 KAT6A (0.77) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL26165840 0.90 KAT7 (1.00) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL24866491 0.88 KAT6A (0.63) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL22817423 0.88 KAT7 (1.00) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL31372020 0.87 KAT6A (0.83) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL31472954 0.87 KAT6A (0.88) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL31371782 0.86 KAT7 (0.90) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL31372058 0.86 KAT6A (0.70) KAT6AKAT7KAT6BKAT8KAT5
SCHEMBL31371939 0.85 KAT6A (0.83) KAT6AKAT7KAT6BKAT8KAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023280182-A1 COMPOUND SERVING AS KAT6 INHIBITOR 杭州英创医药科技有限公司 2023-01-12 — — WO disclosed
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