SCHEMBL24866192

SCHEMBL24866192

CC#Cc1cc(OC)c(S(=O)(=O)Nc2noc3cc(Cn4cccn4)cc(OC)c23)c(OC)c1

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.80
KAT6A Q92794 20/20 0.80
KAT6B Q8WYB5 11/20 0.80
KAT8 Q9H7Z6 11/20 0.80
KAT5 Q92993 10/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24866191 0.93 KAT7 (0.79) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866203 0.91 KAT7 (0.76) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866447 0.91 KAT7 (0.81) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866170 0.90 KAT6A (0.79) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866183 0.90 KAT7 (0.76) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866200 0.89 KAT7 (0.74) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL22828479 0.89 KAT7 (1.00) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866157 0.89 KAT6A (0.79) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866185 0.88 KAT7 (0.72) KAT7KAT6AKAT6BKAT8KAT5
SCHEMBL24866193 0.88 KAT7 (0.73) KAT7KAT6AKAT6BKAT8KAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023280182-A1 COMPOUND SERVING AS KAT6 INHIBITOR 杭州英创医药科技有限公司 2023-01-12 WO disclosed