⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590972 | 1.00 | — | — | |
| SCHEMBL21259887 | 0.76 | — | — | |
| SCHEMBL30400053 | 0.73 | — | — | |
| SCHEMBL24391231 | 0.69 | — | — | |
| SCHEMBL19843562 | 0.69 | — | — | |
| SCHEMBL24387199 | 0.67 | — | — | |
| SCHEMBL31375673 | 0.67 | — | — | |
| SCHEMBL29249254 | 0.65 | — | — | |
| SCHEMBL30341800 | 0.65 | — | — | |
| SCHEMBL19035762 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230010886-A1 | SHP2 INHIBITORS AND USES THEREOF | Suzhou Puhe BioPharma Co., Ltd. (CN) | 2023-01-12 | — | — | US | disclosed |