SCHEMBL2486852

SCHEMBL2486852

N#CC(C#N)CC(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2485371 0.92 USP2 (0.32)
SCHEMBL3038554 0.76
SCHEMBL4594930 0.72
SCHEMBL5984054 0.70 CYP1A2 (0.33)
SCHEMBL291861 0.70
SCHEMBL3163124 0.68 KDM4E (0.30)
SCHEMBL1358616 0.66 KDM4E (0.34)
SCHEMBL291733 0.65
SCHEMBL291817 0.65
SCHEMBL2485309 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901170-B2 Malononitrile compounds BASF SE (DE) 2014-12-02 US disclosed
EP-1697311-B1 NITRILE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL CO (JP) 2011-10-26 EP disclosed
US-20100215777-A1 Malononitrile Compounds BASF SE (DE) 2010-08-26 US disclosed
EP-2176232-A1 1-(AZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2010-04-21 EP disclosed
EP-2152683-A1 SUBSTITUTED AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS Basf Se (DE) 2010-02-17 EP disclosed
US-7662402-B2 contains fluoroalkyl group; insecticides, miticides, nematocides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 US disclosed
US-7662402-B2 contains fluoroalkyl group; insecticides, miticides, nematocides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 US disclosed
EP-2076602-A2 PLANT PRODUTIVITY ENHANCEMENT BY COMBINING CHEMICAL AGENTS WITH TRANSGENIC MODIFICATIONS BASF SE (DE) 2009-07-08 EP disclosed
EP-2061781-A1 SUBSTITUTED 1-(AZOLIN-2-YL)-AMINO-1,2-HETEROCYCLYL-ETHANE COMPOUNDS FOR COMBATING PESTS BASF SE (DE) 2009-05-27 EP disclosed
EP-2044008-A1 MALONONITRILE COMPOUNDS BASF SE (DE) 2009-04-08 EP disclosed
WO-2008129060-A2 PLANT PRODUTIVITY ENHANCEMENT BY COMBINING CHEMICAL AGENTS WITH TRANSGENIC MODIFICATIONS BASF SE (DE) 2008-10-30 WO disclosed
WO-2008074686-A1 SUBSTITUTED 1-(AZOLIN-2-YL)-AMINO-1,2-HETEROCYCLYL-ETHANE COMPOUNDS FOR COMBATING PESTS BASF SE (DE) 2008-06-26 WO disclosed
EP-1893020-A1 DERIVATIVES OF A 1-PHENYLTRIAZOLE AS ANTIPARASITIC AGENTS BASF SE (DE) 2008-03-05 EP disclosed
WO-2007147888-A1 MALONONITRILE COMPOUNDS BASF SE (DE) 2007-12-27 WO disclosed
US-20070112068-A1 Nitrile compound and its use in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-17 US disclosed
US-20070112068-A1 Nitrile compound and its use in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-17 US disclosed
CN-1898200-A Nitrile compound and its pest control use SUMITOMO CHEMICAL CO (JP) 2007-01-17 CN disclosed
WO-2006128867-A1 DERIVATIVES OF A 1-PHENYLTRIAZOLE AS ANTIPARASITIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2006-12-07 WO disclosed
EP-1697311-A1 NITRILE COMPOUND AND ITS USE IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2006-09-06 EP disclosed
WO-2005063694-A1 NITRILE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 WO disclosed