SCHEMBL2487162

SCHEMBL2487162

O=C(O)C=CC(=O)OC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.59
TAAR1 Q96RJ0 2/20 0.48
SLC15A1 P46059 1/20 0.45
EPHX1 P07099 1/20 0.44
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27216283 0.84 HCAR2 (0.64) HCAR2TAAR1ALDH1A1LMNACYP2C19
SCHEMBL3482642 0.84 HCAR2 (0.64) HCAR2TAAR1ALDH1A1LMNACYP2C19
SCHEMBL3482700 0.84 HCAR2 (0.64) HCAR2TAAR1ALDH1A1LMNACYP2C19
SCHEMBL9067635 0.83 EPHX1 (0.46) EPHX1ALDH1A1CYP2D6CYP1A2
SCHEMBL9709425 0.83 HCAR2 (0.58) HCAR2ALDH1A1LMNACYP2C19
SCHEMBL9860853 0.83 HCAR2 (0.58) HCAR2ALDH1A1LMNACYP2C19
SCHEMBL9709424 0.83 HCAR2 (0.58) HCAR2ALDH1A1LMNACYP2C19
SCHEMBL3482637 0.82 HCAR2 (0.61) HCAR2TAAR1SLC15A1ALDH1A1LMNA
SCHEMBL3482646 0.82 HCAR2 (0.61) HCAR2TAAR1SLC15A1ALDH1A1LMNA
SCHEMBL9419971 0.81 HCAR2 (0.60) HCAR2ALDH1A1LMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113845619-A High-refractive-index color-changing monomer and preparation method and application thereof 山东鲁源化工科技有限公司 2021-12-28 CN claimed
CN-113845619-A High-refractive-index color-changing monomer and preparation method and application thereof 山东鲁源化工科技有限公司 2021-12-28 CN disclosed
CN-105085804-A Polystyrene butenedioic acid dibenzyl ester and preparation method and application thereof PETROCHINA CO LTD 2015-11-25 CN disclosed
EP-1410109-B1 PHOTOSENSITIVE RESIN COMPOSITION BASF SE (DE) 2011-10-26 EP disclosed
CN-101139430-B Optical resin composition having excellent impact resistance and method for fabricating optical lens using the same SHIN DAE SPECIALTIES CO LTD 2010-12-22 CN disclosed
CN-101458341-B Combination for stopping uv optical lens and capable of preventing aetiolation in heat treatment process and optical lens using same SHIN DAE SPECIALTIES CO LTD 2010-12-15 CN disclosed
US-7556843-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-07-07 US disclosed
CN-101458341-A Combination for stopping uv optical lens and capable of preventing aetiolation in heat treatment process and optical lens using same SHIN DAE SPECIALTIES CO LTD (KR) 2009-06-17 CN disclosed
US-7425585-B2 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-16 US disclosed
CN-101139430-A Optical resin composition having excellent impact resistance and method for fabricating optical lens using the same SHIN DAE SPECIALTIES CO LTD (KR) 2008-03-12 CN disclosed
CN-1547683-A Photosensitive resin composition �������⻯ѧƷ�ع����޹�˾ 2004-11-17 CN disclosed
US-20040192804-A1 Photosensitive resin composition IGM GROUP B.V. (NL) 2004-09-30 US disclosed
EP-1410109-A1 PHOTOSENSITIVE RESIN COMPOSITION Ciba SC Holding AG (CH) 2004-04-21 EP disclosed
CN-1461417-A Composition for optical material, optical material and plastic lens NOF CORP (JP) 2003-12-10 CN disclosed
CN-1425050-A Antifouling coating material, antifouling coating film, submerged structure, and antifouling method BASF NOF COATINGS CO LTD (JP) 2003-06-18 CN disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
EP-0560267-B1 Isosteric antiherpes peptide derivatives BOEHRINGER INGELHEIM CA LTD (CA) 1998-08-19 EP disclosed
US-5574015-A Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1996-11-12 US disclosed
WO-1993018056-A1 ISOSTERIC ANTIHERPES PEPTIDE DERIVATIVES BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-16 WO disclosed
EP-0560267-A1 Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP disclosed