Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.63 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25972262 | 0.91 | DDB1 (0.66) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30627204 | 0.91 | DDB1 (0.66) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30627368 | 0.90 | DDB1 (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL26447955 | 0.90 | DDB1 (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL21070996 | 0.89 | DDB1 (0.63) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL21070858 | 0.88 | DDB1 (0.62) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL22835224 | 0.88 | DDB1 (0.62) | CRBNDDB1IKZF3 | |
| SCHEMBL28505376 | 0.88 | DDB1 (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL22836092 | 0.88 | DDB1 (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL31727563 | 0.88 | DDB1 (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023283372-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |