⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638946 | 1.00 | — | — | |
| SCHEMBL13806071 | 1.00 | — | — | |
| SCHEMBL2638948 | 1.00 | — | — | |
| SCHEMBL9747493 | 0.99 | — | — | |
| SCHEMBL9747510 | 0.99 | — | — | |
| SCHEMBL9747914 | 0.99 | — | — | |
| SCHEMBL9747918 | 0.99 | — | — | |
| SCHEMBL9747502 | 0.99 | — | — | |
| SCHEMBL9748212 | 0.99 | — | — | |
| SCHEMBL9748223 | 0.99 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4603157-B2 | — | — | 2010-12-22 | — | — | JP | claimed |
| US-6784153-B1 | IDENTIFY MOLECULES THAT CAN BIND TO ORGAN OR TISSUE SPECIFIC MARKERS AND, THEREFORE, CAN HOME TO THE ORGAN OR TISSUE; MEMBRANE DIPEPTIDASE (MDP)-BINDING HOMING MOLECULE, WHICH IS A MOLECULE THAT SELECTIVELY HOMES TO LUNG ENDOTHELIUM | THE BURNHAM INSTITUTE | 2004-08-31 | — | — | US | claimed |
| EP-1062232-A2 | MOLECULES THAT HOME TO VARIOUS SELECTED ORGANS OR TISSUES | The Burnham Institute (US) | 2000-12-27 | — | — | EP | claimed |
| WO-1999046284-A9 | MOLECULES THAT HOME TO VARIOUS SELECTED ORGANS OR TISSUES | BURNHAM INST (US) | 1999-11-18 | — | — | WO | claimed |
| WO-1999046284-A2 | MOLECULES THAT HOME TO VARIOUS SELECTED ORGANS OR TISSUES | THE BURNHAM INSTITUTE (US) | 1999-09-16 | — | — | WO | claimed |
| US-5147868-A | For selectively inhibiting the metabolism of dipeptidase; useful in mixtures with bactericides | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | claimed |
| US-4880793-A | BACTERICIDES, UNSATURATED CARBOXYLIC ACID, AMIDES | MERCK & CO., INC. (US) | 1989-11-14 | — | — | US | claimed |
| US-4668504-A | Use of substituted propenoates to prevent nephrotoxicity of certain antibiotics | MERCK & CO., INC. (US) | 1987-05-26 | — | — | US | claimed |
| EP-0072014-B1 | COMBINATION OF 2-SUBSTITUTED PENEMS WITH DIPEPTIDASE INHIBITORS | MERCK & CO. INC. (US) | 1986-12-30 | — | — | EP | claimed |
| US-4539208-A | Combination of thienamycin-type antibiotics with dipeptidase inhibitors | MERCK & CO., INC. (US) | 1985-09-03 | — | — | US | claimed |
| EP-0028778-B1 | ANTIBACTERIAL COMPOSITIONS COMPRISING A BETA-LACTAM-TYPE COMPOUND AND A 3-SUBSTITUTED PROPENOATE | MERCK & CO. INC. (US) | 1985-01-16 | — | — | EP | claimed |
| EP-0010573-B1 | NOVEL Z-2-ACYLAMINO-3-MONOSUBSTITUTED PROPENIC ACIDS AND THEIR ESTERS AND SALTS, AND PROCESSES FOR PREPARING THEM | MERCK & CO. INC. (US) | 1983-10-19 | — | — | EP | claimed |
| EP-0072014-A1 | Combination of 2-substituted penems with dipeptidase inhibitors | MERCK & CO. INC. (US) | 1983-02-16 | — | — | EP | claimed |
| EP-0007614-B1 | AN ANTIBACTERIAL COMPOSITION OF THIENAMYCIN-TYPE COMPOUND AND A DIPEPTIDASE INHIBITOR | MERCK & CO. INC. (US) | 1983-01-26 | — | — | EP | claimed |
| EP-0028778-A1 | Antibacterial compositions comprising a beta-lactam-type compound and a 3-substituted propenoate | MERCK & CO. INC. (US) | 1981-05-20 | — | — | EP | claimed |
| EP-0007614-A1 | An antibacterial composition of thienamycin-type compound and a dipeptidase inhibitor | MERCK & CO. INC. (US) | 1980-02-06 | — | — | EP | claimed |
| US-20130244929-A1 | BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS | MERCK SHARP & DOHME CORP. | 2013-09-19 | — | — | US | disclosed |
| EP-2544702-A1 | BRIDGED LIPOGLYCOPEPTIDES THAT POTENTIATE THE ACTIVITY OF BETA-LACTAM ANTIBACTERIALS | Merck Sharp & Dohme Corp. (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-0007614-A1 | An antibacterial composition of thienamycin-type compound and a dipeptidase inhibitor | MERCK & CO. INC. (US) | 1980-02-06 | — | — | EP | disclosed |
| EP-0006639-A1 | Crystalline N-formimidoyl thienamycin | MERCK & CO. INC. (US) | 1980-01-09 | — | — | EP | disclosed |