⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942889 | 0.96 | — | — | |
| SCHEMBL30557177 | 0.96 | — | — | |
| SCHEMBL31194820 | 0.96 | — | — | |
| SCHEMBL23740151 | 0.86 | — | — | |
| SCHEMBL20104725 | 0.86 | — | — | |
| SCHEMBL9980155 | 0.84 | — | — | |
| SCHEMBL22214120 | 0.76 | — | — | |
| SCHEMBL22214452 | 0.74 | — | — | |
| SCHEMBL22296005 | 0.74 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL24249016 | 0.74 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230009712-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |