Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IL17A | Q16552 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876444 | 0.97 | MEN1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24875569 | 0.90 | MEN1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24875309 | 0.89 | IL17A (0.48) | MEN1KMT2AIL17ATRPV1JAK1 | |
| SCHEMBL24875084 | 0.88 | PSEN1 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24875083 | 0.88 | PSEN1 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24875475 | 0.88 | IL17A (0.34) | IL17AJAK1 | |
| SCHEMBL24875363 | 0.88 | TSHR (0.39) | MEN1KMT2AL3MBTL1TRPV1JAK1 | |
| SCHEMBL24876177 | 0.88 | IL17A (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24875393 | 0.87 | MEN1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24875305 | 0.87 | MEN1 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283453-A1 | PHENYL ACETAMIDE BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-01-12 | — | — | WO | disclosed |