Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879026 | 0.93 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL24879315 | 0.91 | PTPN11 (0.41) | PTPN11 | |
| SCHEMBL24879274 | 0.88 | PTPN11 (0.38) | PTPN11 | |
| SCHEMBL27459403 | 0.88 | PTPN11 (0.43) | PTPN11 | |
| SCHEMBL30111100 | 0.87 | PTPN11 (0.54) | PTPN11 | |
| SCHEMBL24879085 | 0.87 | PTPN11 (0.54) | PTPN11 | |
| SCHEMBL27459938 | 0.86 | PTPN11 (0.36) | PTPN11 | |
| SCHEMBL27459107 | 0.85 | PTPN11 (0.39) | PTPN11 | |
| SCHEMBL27453185 | 0.84 | PTPN11 (0.46) | PTPN11 | |
| SCHEMBL27216148 | 0.84 | PTPN11 (0.55) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023282702-A1 | SHP2 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-01-12 | — | — | WO | disclosed |