Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 14/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2990371 | 1.00 | CHRM3 (0.53) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL9984393 | 1.00 | CHRM3 (0.53) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL2485505 | 0.96 | CHRM3 (0.55) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL2989743 | 0.96 | CHRM3 (0.55) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL13240867 | 0.93 | CHRM3 (0.57) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3775855 | 0.93 | CHRM3 (0.57) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2507102 | 0.93 | CHRM3 (0.57) | CHRM3CHRM2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL2484663 | 0.89 | CHRM2 (0.52) | CHRM3CHRM2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL2992250 | 0.89 | CHRM2 (0.52) | CHRM3CHRM2CHRM1 | |
| SCHEMBL13240865 | 0.88 | CHRM3 (0.62) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | claimed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | claimed |