Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24880761 | 0.90 | ACACB (0.47) | HRH3ACACBOGADGAT2POLB | |
| SCHEMBL24881050 | 0.90 | ACACB (0.47) | HRH3ACACBOGADGAT2POLB | |
| SCHEMBL15994455 | 0.86 | OGA (0.49) | HRH3ACACBOGAPOLBMAPT | |
| SCHEMBL4211279 | 0.86 | OGA (0.49) | HRH3ACACBOGAAOC3POLB | |
| SCHEMBL753762 | 0.85 | OGA (0.48) | HRH3ACACBOGAPOLBMAPT | |
| SCHEMBL15994451 | 0.85 | OGA (0.48) | HRH3ACACBOGAPOLBMAPT | |
| SCHEMBL24126692 | 0.84 | OGA (0.53) | HRH3ACACBOGAPOLBMAPT | |
| SCHEMBL2622717 | 0.84 | OGA (0.47) | HRH3ACACBOGAPOLBMAPT | |
| SCHEMBL12952642 | 0.83 | POLB (0.54) | ACACBOGADGAT2POLBMAPT | |
| SCHEMBL6984326 | 0.83 | MAPT (0.57) | HRH3ACACBOGAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |