Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.61 |
| ▸ | GRM5 | P41594 | 11/20 | 0.61 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590064 | 0.89 | GRM1 (0.56) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL2268829 | 0.85 | GRM1 (0.59) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL30439311 | 0.85 | GRM1 (0.59) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL31639564 | 0.85 | GRM1 (0.59) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL15176153 | 0.85 | GRM1 (0.59) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL24891853 | 0.83 | GRM1 (0.57) | GRM1GRM5PDK4NAMPTWNT3A | |
| SCHEMBL2264461 | 0.82 | GRM1 (0.56) | GRM1GRM5PDK4NAMPTWNT3A | |
| SCHEMBL31701242 | 0.81 | GRM1 (0.55) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL64945 | 0.81 | GRM1 (0.55) | GRM1GRM5PDK4NAMPTHTR6 | |
| SCHEMBL13472360 | 0.81 | GRM1 (0.54) | GRM1GRM5PDK4NAMPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594666-B | Synthesis and application of phosphatase degradation agent | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| EP-4368614-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | Hinova Pharmaceuticals Inc. (CN) | 2024-05-15 | — | — | EP | disclosed |
| CN-115594666-A | Synthesis and application of phosphatase degrading agent | 海创药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |