Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5642066 | 0.89 | CYP1A2 (0.64) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL1645260 | 0.81 | CYP1A2 (0.56) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL13197220 | 0.81 | CYP1A2 (0.56) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29524945 | 0.81 | CYP1A2 (0.56) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5169193 | 0.80 | CYP1A2 (0.55) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29385070 | 0.79 | MAPK1 (0.47) | CYP1A2MAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL19900024 | 0.79 | MAPK1 (0.47) | CYP1A2MAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL29549951 | 0.79 | CYP1A2 (0.50) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL23529953 | 0.79 | CYP1A2 (0.50) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL12228821 | 0.79 | CYP1A2 (0.53) | CYP1A2MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |