Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.53 |
| ▸ | CSF1R | P07333 | 2/20 | 0.52 |
| ▸ | ROR1 | Q01973 | 6/20 | 0.52 |
| ▸ | ABL2 | P42684 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290930 | 1.00 | ABL1 (0.53) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL24885568 | 0.91 | ABL1 (0.46) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL30078301 | 0.87 | ABL1 (0.57) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL24885421 | 0.87 | ABL1 (0.57) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL24885891 | 0.83 | ROR1 (0.57) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL30078084 | 0.83 | ROR1 (0.57) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL31290938 | 0.78 | ABL1 (0.48) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL24885737 | 0.78 | ABL1 (0.48) | ABL1CSF1RROR1ABL2CYP3A4 | |
| SCHEMBL24885425 | 0.75 | NPY5R (0.33) | CSF1RROR1EGFRNR3C1PDGFRB | |
| SCHEMBL24885769 | 0.74 | NPY5R (0.49) | NR3C1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |