⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25086983 | 0.79 | GRIN2D (0.32) | — | |
| SCHEMBL16170229 | 0.79 | — | — | |
| SCHEMBL18199679 | 0.76 | — | — | |
| SCHEMBL18120030 | 0.76 | ATM (0.31) | — | |
| SCHEMBL16625645 | 0.76 | ATM (0.31) | — | |
| SCHEMBL23773733 | 0.76 | ATM (0.31) | — | |
| SCHEMBL21391958 | 0.76 | ATM (0.31) | — | |
| SCHEMBL21469432 | 0.75 | — | — | |
| SCHEMBL26268389 | 0.73 | ATM (0.32) | — | |
| SCHEMBL27117028 | 0.70 | ATM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018162-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240018162-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20230012560-A1 | HEPATITIS B ANTIVIRAL AGENTS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2023-01-19 | — | — | US | disclosed |