Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 8/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17002864 | 1.00 | KDM1A (0.67) | KDM1AMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL17002866 | 1.00 | KDM1A (0.67) | KDM1AMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL17002957 | 0.88 | KDM1A (0.68) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL17002703 | 0.88 | KDM1A (0.68) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL17003327 | 0.87 | KDM1A (0.61) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL17003330 | 0.87 | KDM1A (0.61) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL24890660 | 0.85 | KDM1A (0.51) | KDM1AMAOBMAOAALDH1A1TLR2 | |
| SCHEMBL24890721 | 0.85 | KDM1A (0.51) | KDM1AMAOBMAOAALDH1A1TLR2 | |
| SCHEMBL24890878 | 0.85 | KDM1A (0.51) | KDM1AMAOBMAOAALDH1A1HPGD | |
| SCHEMBL15091433 | 0.85 | KDM1A (0.76) | KDM1AMAOBMAOASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |