SCHEMBL24890682

SCHEMBL24890682

Nc1ccccc1NC(=O)c1ccc(NC(=O)OCc2ccc([C@H]3C[C@@H]3NCC3COC3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 19/20 0.57
MAOA P21397 2/20 0.57
HDAC1 Q13547 1/20 0.57
HDAC2 Q92769 1/20 0.57
RCOR1 Q9UKL0 1/20 0.54
MAOB P27338 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24890731 1.00 KDM1A (0.57) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890542 0.93 KDM1A (0.64) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890619 0.93 KDM1A (0.64) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890744 0.93 KDM1A (0.64) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890541 0.93 KDM1A (0.64) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890679 0.93 KDM1A (0.64) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890665 0.92 KDM1A (0.59) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890562 0.92 KDM1A (0.59) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890735 0.92 KDM1A (0.59) KDM1AMAOAHDAC1HDAC2RCOR1
SCHEMBL24890657 0.88 KDM1A (0.56) KDM1AMAOAHDAC1HDAC2RCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284651-A1 N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF 南京明德新药研发有限公司 2023-01-19 WO disclosed