Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15934124 | 0.81 | MAPT (0.46) | TSHRMAPTGAA | |
| SCHEMBL6912374 | 0.80 | SETD7 (0.46) | TSHRUSP2 | |
| SCHEMBL10196598 | 0.80 | SETD7 (0.46) | TSHRUSP2 | |
| SCHEMBL10196611 | 0.80 | SETD7 (0.46) | TSHRUSP2 | |
| SCHEMBL4252900 | 0.79 | TSHR (0.62) | TSHRMAPTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL28424171 | 0.79 | TSHR (0.39) | TSHRDRD2MAPTGSK3BDYRK1A | |
| SCHEMBL16009877 | 0.79 | TSHR (0.39) | TSHRDRD2MAPTGSK3BDYRK1A | |
| SCHEMBL31597599 | 0.78 | TSHR (0.46) | TSHRCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL799032 | 0.78 | CYP1A2 (0.43) | TSHRMAPTGSK3BDYRK1AGAA | |
| SCHEMBL4248088 | 0.78 | TSHR (0.39) | TSHRMAPTGSK3BDYRK1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |