SCHEMBL24890782

SCHEMBL24890782

Cc1ccc(N[C@@H]2CCC(=O)NC2=O)cn1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.68
CRBN Q96SW2 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21946764 1.00 DDB1 (0.68) DDB1CRBN
SCHEMBL23551217 0.83 DDB1 (0.63) DDB1CRBN
SCHEMBL25627106 0.83 DDB1 (0.59) DDB1CRBN
SCHEMBL23593988 0.83 DDB1 (0.59) DDB1CRBN
SCHEMBL25627104 0.83 DDB1 (0.59) DDB1CRBN
SCHEMBL24890786 0.83 DDB1 (0.59) DDB1CRBN
SCHEMBL23551580 0.83 DDB1 (0.59) DDB1CRBN
SCHEMBL24890785 0.83 DDB1 (0.59) DDB1CRBN
SCHEMBL21965809 0.81 DDB1 (1.00) DDB1CRBN
SCHEMBL31101565 0.81 DDB1 (0.60) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287928-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY NURIX THERAPEUTICS, INC. (US) 2023-01-19 WO disclosed