Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 9/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | WNT1 | P04628 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24890685 | 0.85 | HDAC2 (0.52) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL24890696 | 0.83 | HDAC2 (0.58) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL24890948 | 0.79 | HDAC3 (0.55) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL23077104 | 0.78 | HDAC6 (0.52) | HDAC1HDAC3HDAC8HDAC6WNT1 | |
| SCHEMBL26484688 | 0.77 | HDAC6 (0.51) | HDAC1HDAC3HDAC8HDAC6WNT1 | |
| SCHEMBL2830015 | 0.75 | HDAC1 (0.74) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL12487004 | 0.75 | KDM1A (0.53) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL12486951 | 0.75 | KDM1A (0.53) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL12684542 | 0.75 | KDM1A (0.53) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30620400 | 0.75 | HSD17B3 (0.55) | HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |