Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181019 | 1.00 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1HTTPOLB | |
| SCHEMBL24891761 | 0.93 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1HTTPOLB | |
| SCHEMBL24669978 | 0.88 | MAPT (0.64) | MAPTSMN1; SMN2ALDH1A1HTTRAB9A | |
| SCHEMBL24891879 | 0.88 | MAPT (0.64) | MAPTSMN1; SMN2ALDH1A1HTTRAB9A | |
| SCHEMBL30180906 | 0.84 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1HTTPOLB | |
| SCHEMBL24891896 | 0.84 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1HTTPOLB | |
| SCHEMBL24892344 | 0.83 | CHIA (0.51) | MAPTSMN1; SMN2ALDH1A1HTTRAB9A | |
| SCHEMBL24892272 | 0.81 | NPC1 (0.63) | MAPTSMN1; SMN2ALDH1A1POLBRAB9A | |
| SCHEMBL24891642 | 0.81 | MAPT (0.61) | MAPTSMN1; SMN2ALDH1A1HTTRAB9A | |
| SCHEMBL30182512 | 0.81 | MAPT (0.61) | MAPTSMN1; SMN2ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |