Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM6A | O15550 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179360 | 0.76 | ELANE (0.64) | ELANEKDM4EKDM6BKDM6ATET3 | |
| SCHEMBL1716468 | 0.74 | POLB (0.43) | KDM4EHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28576274 | 0.73 | POLB (0.42) | KDM4EHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27807548 | 0.73 | POLB (0.42) | KDM4EHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL20674192 | 0.72 | DYRK1A (0.49) | ELANEKDM4EKDM6BKDM4CL3MBTL1 | |
| SCHEMBL27728704 | 0.71 | ELANE (0.40) | ELANEKDM4EKDM6BKDM6ATET3 | |
| Sulfuric Acid SCHEMBL17028780 | 0.70 | POLB (0.39) | ELANEKDM4EHTTMEN1KMT2A | |
| SCHEMBL27947846 | 0.70 | ELANE (0.46) | ELANEKDM4EFEN1MEN1KMT2A | |
| SCHEMBL12413040 | 0.68 | KDM4E (0.42) | ELANEKDM4EKDM6BKDM6ATET3 | |
| SCHEMBL28319416 | 0.68 | ELANE (0.36) | ELANEKDM4EFEN1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379549-B1 | 7-AZAINDIRUBINS, 7'-AZAINDIRUBINS, 7-7'-DIAZAINDIRUBIN AND THE CORRESPONDING 3'-OXIME ETHER DERIVATES: PRODUCTION THEREOF, THEIR PRODUCTION AND USE AS A MEDICAMENT | EISENBRAND GERHARD (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-2379549-A1 | 7-AZAINDIRUBINS, 7'AZAINDIRUBINS, 7,7'-DIAZAINDIRUBINS AND THE CORRESPONDING 3'-OXIME ETHER DERIVATIVES THEREOF, THEIR PRODUCTION AND USE AS A MEDICAMENT | Eisenbrand, Gerhard (DE) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010072399-A1 | 7-AZAINDIRUBINS, 7'AZAINDIRUBINS, 7,7'-DIAZAINDIRUBINS AND THE CORRESPONDING 3'-OXIME ETHER DERIVATIVES THEREOF, THEIR PRODUCTION AND USE AS A MEDICAMENT | EISENBRAND GERHARD (DE) | 2010-07-01 | — | — | WO | disclosed |
| EP-2199292-A1 | 7-azaindirubins, 7'-azaindirubins, 7-7'-diazaindirubin and the corresponding 3'-oxime ether derivates: production thereof, their production and use as a medicament | Technische Universität Kaiserlautern (DE) | 2010-06-23 | — | — | EP | disclosed |