⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693995 | 1.00 | — | — | |
| SCHEMBL21410865 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11059768 | 0.97 | GAA (0.43) | — | |
| SCHEMBL11172703 | 0.97 | GAA (0.43) | — | |
| Fluoride SCHEMBL10970483 | 0.97 | GAA (0.48) | — | |
| Bromide SCHEMBL11820164 | 0.97 | GAA (0.43) | — | |
| SCHEMBL10864959 | 0.81 | HPGD (0.47) | — | |
| SCHEMBL1136246 | 0.79 | — | — | |
| SCHEMBL11616228 | 0.78 | FFAR3 (0.38) | — | |
| SCHEMBL8523602 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764888-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) | 2009-10-15 | — | — | US | claimed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | claimed |
| EP-1868982-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | The Governors of the University of Alberta (CA) | 2007-12-26 | — | — | EP | claimed |
| WO-2006117686-A2 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2006-11-09 | — | — | WO | claimed |
| US-20050182133-A1 | Compounds that stimulate glucose utilization and methods of use | UNIVERSITY OF ALBERTA (CA) | 2005-08-18 | — | — | US | claimed |
| EP-0024172-B1 | ANTITUMOR AND IMMUNOSUPPRESSIVE 4-CARBAMOYLIMIDAZOLIUM-5-OLATE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-11 | — | — | EP | claimed |
| US-20250243177-A1 | sGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| US-20250179043-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-06-05 | — | — | US | disclosed |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250154124-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-15 | — | — | US | disclosed |
| CN-118715212-A | Preparation of N- (1-methylcyclopropyl) -2- (3-pyridinyl) -2H-indazole-4-carboxamide and intermediates thereof | FMC公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118715213-A | Process for preparing N- (1-methylcyclopropyl) -2- (3-pyridinyl) -2H-indazole-4-carboxamide and intermediates thereof | FMC公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-0089011-B1 | PROCESS FOR THE PREPARATION OF 5-OXONITRILES | Degussa Aktiengesellschaft (DE) | 1985-07-10 | — | — | EP | disclosed |
| EP-0043950-B1 | 1-METHYL-2-CHLORO-CYCLOPROPANECARBOXYLIC ACID AND ITS ESTERS, PROCESS FOR THEIR PREPARATION | Degussa Aktiengesellschaft (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0089011-A1 | Process for the preparation of 5-oxonitriles | Degussa Aktiengesellschaft (DE) | 1983-09-21 | — | — | EP | disclosed |
| US-4390719-A | 1-Methyl-2-chlorocyclopropanecarboxylic acid and its ester | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1983-06-28 | — | — | US | disclosed |
| EP-0043950-A1 | 1-Methyl-2-chloro-cyclopropanecarboxylic acid and its esters, process for their preparation | Degussa Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |
| US-4256752-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-03-17 | — | — | US | disclosed |
| US-3954730-A | ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |