Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681036 | 1.00 | KRAS (0.33) | KRAS | |
| SCHEMBL26501987 | 0.91 | — | — | |
| SCHEMBL24616526 | 0.86 | KRAS (0.35) | KRAS | |
| SCHEMBL24858463 | 0.86 | KRAS (0.35) | KRAS | |
| SCHEMBL26734669 | 0.85 | KRAS (0.33) | KRAS | |
| SCHEMBL26727836 | 0.85 | — | — | |
| SCHEMBL24680309 | 0.85 | KRAS (0.33) | KRAS | |
| SCHEMBL26899448 | 0.85 | KRAS (0.33) | KRAS | |
| SCHEMBL26885334 | 0.85 | — | — | |
| SCHEMBL24680284 | 0.84 | KRAS (0.31) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024055112-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023284730-A1 | ALKYLIDENE DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |