Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 19/20 | 0.81 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30221275 | 1.00 | ALK (0.81) | ALKEGFR | |
| SCHEMBL16752910 | 0.90 | ALK (1.00) | ALK | |
| SCHEMBL16769538 | 0.90 | ALK (1.00) | ALK | |
| SCHEMBL30221574 | 0.90 | ALK (0.82) | ALKEGFR | |
| SCHEMBL29229096 | 0.88 | ALK (0.76) | ALKEGFR | |
| SCHEMBL30221317 | 0.88 | ALK (0.76) | ALKEGFR | |
| SCHEMBL28584062 | 0.88 | EGFR (0.80) | ALKEGFR | |
| SCHEMBL16752989 | 0.87 | ALK (1.00) | ALK | |
| SCHEMBL17531020 | 0.87 | ALK (0.83) | ALKEGFR | |
| SCHEMBL18334855 | 0.87 | ALK (0.93) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |