Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31503155 | 1.00 | EGFR (0.46) | EGFRCDK7CCNHKCNH2PTK2 | |
| SCHEMBL24900592 | 0.93 | EGFR (0.46) | EGFRCDK7CCNHKCNH2PTK2 | |
| SCHEMBL30221405 | 0.93 | EGFR (0.47) | EGFRCDK7CCNHKCNH2IGF1R | |
| SCHEMBL24900803 | 0.93 | EGFR (0.47) | EGFRCDK7CCNHKCNH2IGF1R | |
| SCHEMBL30221464 | 0.91 | EGFR (0.48) | EGFRKCNH2IGF1R | |
| SCHEMBL24900798 | 0.91 | EGFR (0.48) | EGFRKCNH2IGF1R | |
| SCHEMBL30221377 | 0.90 | EGFR (0.56) | EGFRKCNH2IGF1R | |
| SCHEMBL24900468 | 0.90 | EGFR (0.56) | EGFRKCNH2IGF1R | |
| SCHEMBL24900581 | 0.87 | EGFR (0.46) | EGFRCDK7CCNHKCNH2PTK2 | |
| SCHEMBL30221386 | 0.87 | EGFR (0.46) | EGFRCDK7CCNHKCNH2PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |