Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CCNK | O75909 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CCNH | P51946 | 2/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900358 | 0.89 | DYRK1A (0.53) | DYRK1ANFATC1GSK3BRPS6KA5HTR2A | |
| SCHEMBL30957550 | 0.89 | DYRK1A (0.53) | DYRK1ANFATC1GSK3BRPS6KA5HTR2A | |
| SCHEMBL24900727 | 0.88 | RPS6KA5 (0.56) | DYRK1ANFATC1GSK3BRPS6KA5HTR2A | |
| SCHEMBL24900454 | 0.86 | CCNT1 (0.43) | DYRK1ANFATC1GSK3BRPS6KA5CCNT1 | |
| SCHEMBL30957556 | 0.86 | CCNT1 (0.43) | DYRK1ANFATC1GSK3BRPS6KA5CCNT1 | |
| SCHEMBL30221346 | 0.85 | DYRK1A (0.47) | DYRK1ANFATC1GSK3BRPS6KA5CCNT1 | |
| SCHEMBL24900426 | 0.85 | DYRK1A (0.47) | DYRK1ANFATC1GSK3BRPS6KA5CCNT1 | |
| SCHEMBL30957452 | 0.85 | RPS6KA5 (0.48) | DYRK1ARPS6KA5CCNT1CCNKCCNE1 | |
| SCHEMBL24900631 | 0.85 | RPS6KA5 (0.48) | DYRK1ARPS6KA5CCNT1CCNKCCNE1 | |
| SCHEMBL24900677 | 0.84 | CCNT1 (0.55) | RPS6KA5HTR2ACCNT1CCNKCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |