SCHEMBL24901017

SCHEMBL24901017

c1ccc(-c2nc(-c3ccc4c5ccccc5c5ccccc5c4c3)nc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccc(-c7ccccc7)c7c6oc6ccccc67)c5c43)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.33
ALDH1A1 P00352 5/20 0.33
TSHR P16473 4/20 0.33
LMNA P02545 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 3/20 0.33
MAPK1 P28482 2/20 0.33
POLB P06746 2/20 0.33
CDC14B O60729 2/20 0.32
CDC14A Q9UNH5 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
HPGD P15428 1/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
CYP17A1 P05093 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
ALOX12 P18054 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24901001 0.94 MAPT (0.36) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24739478 0.89 PRKDC (0.34) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24738311 0.88 MAPT (0.35) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24901003 0.88 CDC14B (0.38) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24738682 0.87 MAPT (0.33) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL25459667 0.86 PRKDC (0.36) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24738659 0.86 PRKDC (0.36) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24738681 0.86 MAPT (0.32) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24740192 0.86 MAPT (0.32) MAPTALDH1A1TSHRLMNAKDM4E
SCHEMBL24901058 0.85 MAPT (0.34) MAPTALDH1A1TSHRLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287026-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-01-19 WO disclosed