Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.46 |
| ▸ | HTR2C | P28335 | 6/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310206 | 0.82 | HTR2A (0.63) | HTR2AHTR2CP2RX7ACACBHTR7 | |
| SCHEMBL30515265 | 0.82 | HTR2A (0.63) | HTR2AHTR2CP2RX7ACACBHTR7 | |
| SCHEMBL23519846 | 0.80 | KMT2A (0.48) | HTR2AHTR2CFGFR1FGFR4KMO | |
| SCHEMBL18911998 | 0.79 | HTR2A (0.40) | HTR2AHTR2CKDM1ACYP1A2CYP3A4 | |
| SCHEMBL18912161 | 0.79 | HTR2A (0.40) | HTR2AHTR2CKDM1ACYP1A2CYP3A4 | |
| SCHEMBL18911877 | 0.77 | HTR2C (0.53) | HTR2AHTR2CP2RX7ACACBHTR7 | |
| SCHEMBL3481149 | 0.77 | HTR2A (0.49) | HTR2AHTR2CP2RX7ACACBHTR7 | |
| SCHEMBL18912153 | 0.76 | CYP2A6 (0.41) | HTR2AHTR2C | |
| SCHEMBL21936808 | 0.76 | KRAS (0.41) | HTR2AHTR2CKDM1A | |
| SCHEMBL18912005 | 0.76 | GRIN2B (0.46) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381896-B1 | BIPHENYL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-01-18 | — | — | EP | disclosed |