Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 9/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 7/20 | 0.37 |
| ▸ | JAK1 | P23458 | 7/20 | 0.37 |
| ▸ | JAK3 | P52333 | 3/20 | 0.37 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.37 |
| ▸ | PAK4 | O96013 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | LTK | P29376 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | CLK2 | P49760 | 2/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24902117 | 0.92 | JAK2 (0.48) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL26610798 | 0.92 | JAK2 (0.48) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL24902007 | 0.82 | JAK1 (0.48) | JAK2JAK1JAK3TYK2RET | |
| SCHEMBL24902172 | 0.80 | JAK2 (0.46) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL27200387 | 0.80 | JAK2 (0.46) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL26611582 | 0.80 | JAK2 (0.52) | JAK2JAK1JAK3TYK2DAPK3 | |
| SCHEMBL24902027 | 0.80 | JAK2 (0.52) | JAK2JAK1JAK3TYK2DAPK3 | |
| SCHEMBL24902120 | 0.80 | JAK2 (0.52) | JAK2JAK1JAK3TYK2DAPK3 | |
| SCHEMBL26610418 | 0.79 | JAK2 (0.45) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL27246134 | 0.76 | JAK2 (0.47) | PTGS1PTGS2OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001045-A9 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海椿安生物医药科技有限公司 | 2023-10-26 | — | — | WO | disclosed |
| WO-2023001045-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海椿安生物医药科技有限公司 | 2023-01-26 | — | — | WO | disclosed |