Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 14/20 | 0.77 |
| ▸ | MME | P08473 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352140 | 0.87 | CETP (1.00) | CETPMME | |
| SCHEMBL18602182 | 0.87 | CETP (1.00) | CETPMME | |
| SCHEMBL527973 | 0.87 | CETP (1.00) | CETPMME | |
| Hydrogen Sulfide SCHEMBL28096222 | 0.86 | CETP (0.97) | CETPMME | |
| SCHEMBL2490218 | 0.85 | CETP (0.64) | CETP | |
| SCHEMBL2486998 | 0.83 | CETP (0.78) | CETP | |
| SCHEMBL9943229 | 0.81 | CETP (0.87) | CETPMME | |
| SCHEMBL14408429 | 0.80 | CETP (0.77) | CETP | |
| SCHEMBL1534085 | 0.79 | CETP (0.76) | CETPMME | |
| SCHEMBL18011036 | 0.78 | CETP (0.78) | CETPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379492-A1 | CYCLOHEXANECARBOXAMIDE DERIVATIVES USEFUL AS INHIBITORS OF CHOLESTERYL ESTER TRANSFER PROTEIN | F. Hoffmann-La Roche AG (CH) | 2011-10-26 | — | — | EP | disclosed |