Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489080 | 0.90 | CHRM1 (0.62) | CHRM1CHRM5 | |
| SCHEMBL2488401 | 0.89 | CHRM1 (0.62) | CHRM1CHRM5 | |
| SCHEMBL2484371 | 0.88 | CHRM1 (0.59) | CHRM1CHRM5 | |
| SCHEMBL2490478 | 0.86 | CHRM1 (1.00) | CHRM1CHRM5 | |
| SCHEMBL2487495 | 0.85 | CHRM1 (0.55) | CHRM1 | |
| SCHEMBL16597420 | 0.83 | CHRM1 (0.88) | CHRM1CHRM5 | |
| SCHEMBL16597386 | 0.83 | CHRM1 (0.74) | CHRM1CHRM5 | |
| SCHEMBL16597646 | 0.81 | CHRM1 (0.74) | CHRM1CHRM5 | |
| SCHEMBL19134382 | 0.81 | CHRM1 (0.77) | CHRM1CHRM5 | |
| SCHEMBL16597436 | 0.81 | CHRM1 (0.77) | CHRM1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2037739-B1 | BENZYL-SUBSTITUTED QUINOLONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2011-10-26 | — | — | EP | claimed |