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SCHEMBL24905259

SCHEMBL24905259

c1ccc(N(c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2ccccc2C32c3ccccc3-c3ccccc32)c2cccc3c2-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ OPRK1 P41145 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ PDK2 Q15119 2/20 0.32
▸ ESR1 P03372 1/20 0.31
▸ ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24904685 0.95 KDM4E (0.38) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL24904693 0.95 PDK2 (0.34) PDK2
SCHEMBL15213852 0.94 KDM4E (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL23072273 0.94 KDM4E (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854420 0.94 KDM4E (0.39) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL23278254 0.93 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25563184 0.93 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25563684 0.93 KDM4E (0.38) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854071 0.92 MEN1 (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL24646510 0.92 PDK2 (0.34) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 — — US disclosed