Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24757739 | 0.95 | AKR1C3 (0.33) | PTGER4AKR1C3AKR1C2EPHX2PTGDR2 | |
| SCHEMBL24757762 | 0.88 | CHRNA7 (0.33) | PTGER4KDM4C | |
| SCHEMBL24758432 | 0.87 | PDE8B (0.40) | — | |
| SCHEMBL24758402 | 0.86 | PTGER4 (0.31) | PTGER4 | |
| SCHEMBL24758978 | 0.84 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL24758150 | 0.83 | CHRNA7 (0.30) | — | |
| SCHEMBL30975967 | 0.83 | CHRNA7 (0.30) | — | |
| SCHEMBL30975935 | 0.83 | CHRNA7 (0.30) | — | |
| SCHEMBL24757238 | 0.83 | — | — | |
| SCHEMBL24758319 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025025-A1 | SUBSTITUTED PYRAZOLE AMIDES | GRUENENTHAL GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025025-A1 | SUBSTITUTED PYRAZOLE AMIDES | SCN8A, SCN1A, SCN7A | PTGER4 633/4885P2RY14 165/4885KDM4C 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.