⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401189 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL20268360 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL20268358 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL25403230 | 0.97 | — | — | |
| SCHEMBL8886206 | 0.84 | — | — | |
| SCHEMBL2505750 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL1478454 | 0.81 | CYP2D6 (0.36) | — | |
| SCHEMBL26670750 | 0.73 | — | — | |
| SCHEMBL20640563 | 0.73 | — | — | |
| SCHEMBL26670753 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166595-A1 | PROCESS FOR THE PREPARATION OF BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS | GENENTECH, INC. (US) | 2024-05-23 | — | — | US | disclosed |
| EP-4347574-A1 | PROCESS FOR THE PREPARATION OF BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS | Genentech, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117377660-A | Process for the preparation of benzoxazepine oxazolidinone compounds | 基因泰克公司 | 2024-01-09 | — | — | CN | disclosed |
| EP-4165023-A1 | INHIBITORS OF APOL1 AND USE OF THE SAME | Vertex Pharmaceuticals Incorporated (US) | 2023-04-19 | — | — | EP | disclosed |
| CN-115867532-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20230014907-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2023-01-19 | — | — | US | disclosed |
| WO-2022251567-A1 | PROCESS FOR THE PREPARATION OF BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS | GENENTECH, INC. (US) | 2022-12-01 | — | — | WO | disclosed |