SCHEMBL2490882

SCHEMBL2490882

O=C(O)c1ccnc(-c2nccc(C(=O)O)c2C(=O)O)c1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
TDP1 Q9NUW8 2/20 0.54
ASPH Q12797 3/20 0.53
KDM8 Q8N371 3/20 0.53
KDM4A O75164 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
EGLN1 Q9GZT9 2/20 0.43
HIF1AN Q9NWT6 2/20 0.43
RAB9A P51151 1/20 0.43
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.42
ALOX15 P16050 2/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
BLM P54132 1/20 0.42
AGER Q15109 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4C Q9H3R0 6/20 0.41
NAPRT Q6XQN6 2/20 0.41
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28459405 0.86 KDM4E (0.50) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL87737 0.82 KDM4E (0.50) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL8140599 0.82 KDM4E (0.39) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL31663481 0.80 KDM4E (0.49) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL8952364 0.80 KDM4E (0.49) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL28556199 0.80 KDM4E (0.49) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL19857476 0.80 KDM4E (0.52) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL547943 0.80 KDM4E (0.68) KDM4ETDP1ASPHKDM8KDM4A
SCHEMBL1539363 0.79 KDM4E (0.47) KDM4ETDP1KDM4AL3MBTL1ALDH1A1
SCHEMBL1245016 0.78 SMN1; SMN2 (0.57) KDM4ETDP1ASPHKDM8KDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112755968-A MOFs fiber membrane for adsorbing micro-nano plastics in trapped water and preparation method thereof 廊坊师范学院 2021-05-07 CN claimed
EP-4341349-A1 METHODS OF COATING METAL SUBSTRATES AND MAKING METAL PACKAGING, COATED METAL SUBSTRATES, METAL PACKAGING, AND POWDER COATING COMPOSITION SYSTEMS SWIMC LLC (US) 2024-03-27 EP disclosed
EP-4341007-A1 METHODS OF COATING SUBSTRATES AND COATED SUBSTRATES Swimc LLC (US) 2024-03-27 EP disclosed
EP-4341008-A1 LIQUID OR AEROSOL JET COATING COMPOSITIONS FOR SUBSTRATES, COATED SUBSTRATES AND METHODS OF COATING Swimc LLC (US) 2024-03-27 EP disclosed
CN-112755968-B Application of MOFs fiber membrane in adsorption of micro-nano plastic in trapped water 廊坊师范学院 2022-09-09 CN disclosed
CN-112755968-A MOFs fiber membrane for adsorbing micro-nano plastics in trapped water and preparation method thereof 廊坊师范学院 2021-05-07 CN disclosed
EP-2379311-A2 POLYESTER POWDER COMPOSITIONS, METHODS AND ARTICLES Valspar Sourcing, Inc. (US) 2011-10-26 EP disclosed
WO-2010075395-A2 POLYESTER POWDER COMPOSITIONS, METHODS AND ARTICLES VALSPAR SOURCING, INC. (US) 2010-07-01 WO disclosed
US-6498217-B1 HIGH MOLECULAR WEIGHT; FLOWABILITY; CRYSTALLINITY; STIFF; MOLDINGS BAYER AKTIENGESELLSHAFT (DE) 2002-12-24 US disclosed
EP-1117725-A1 ACCELERATOR FOR THE PRODUCTION OF POLYAMIDES FROM AMINONITRILES BASF AKTIENGESELLSCHAFT (DE) 2001-07-25 EP disclosed
EP-1056798-A1 METHOD FOR PRODUCING POLYAMIDES FROM AMINO CARBOXYLIC ACID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2000-12-06 EP disclosed
EP-1053275-A1 CONTINUOUS METHOD FOR PRODUCING POLYAMIDES FROM AMINONITRILES BASF AKTIENGESELLSCHAFT (DE) 2000-11-22 EP disclosed
WO-2000020488-A1 ACCELERATOR FOR THE PRODUCTION OF POLYAMIDES FROM AMINONITRILES BASF AKTIENGESELLSCHAFT (DE) 2000-04-13 WO disclosed
WO-1999043734-A1 METHOD FOR PRODUCING POLYAMIDES FROM AMINO CARBOXYLIC ACID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1999-09-02 WO disclosed
WO-1999038906-A1 CONTINUOUS METHOD FOR PRODUCING POLYAMIDES FROM AMINONITRILES BASF AKTIENGESELLSCHAFT (DE) 1999-08-05 WO disclosed