SCHEMBL24909007

SCHEMBL24909007

CCCNC(=O)C(CC(C)C)N1C(=O)c2cc(Oc3cc(C)cc(C)c3)c3c4c(Oc5cc(C)cc(C)c5)cc5c6c(cc(Oc7cc(C)cc(C)c7)c(c7c(Oc8cc(C)cc(C)c8)cc(c2c37)C1=O)c64)C(=O)N(C(CC(C)C)C(=O)NCCC)C5=O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
CARM1 Q86X55 2/20 0.37
PRMT6 Q96LA8 2/20 0.37
ALDH1A1 P00352 3/20 0.37
GAA P10253 1/20 0.37
USP2 O75604 2/20 0.34
TSHR P16473 1/20 0.34
GCK P35557 1/20 0.34
MCL1 Q07820 3/20 0.33
THRB P10828 1/20 0.33
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
LMNA P02545 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908678 0.86 SMN1; SMN2 (0.44) SMN1; SMN2CARM1PRMT6TSHRTP53
SCHEMBL24705860 0.85 SMN1; SMN2 (0.41) SMN1; SMN2CARM1PRMT6ALDH1A1GAA
SCHEMBL24909107 0.82 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1USP2THRBHSD17B10
SCHEMBL24909098 0.80 USP2 (0.46) SMN1; SMN2ALDH1A1GAAUSP2TSHR
SCHEMBL24909013 0.79 SMN1; SMN2 (0.38) SMN1; SMN2CARM1PRMT6ALDH1A1TSHR
SCHEMBL24739817 0.79 GAA (0.34) SMN1; SMN2ALDH1A1GAAUSP2TSHR
SCHEMBL24705392 0.78 SMN1; SMN2 (0.39) SMN1; SMN2
SCHEMBL24909214 0.77 SMN1; SMN2 (0.35) SMN1; SMN2CARM1PRMT6ALDH1A1GAA
SCHEMBL24705268 0.77 USP2 (0.37) SMN1; SMN2ALDH1A1GAAUSP2TSHR
SCHEMBL24705626 0.76 MCL1 (0.45) ALDH1A1GAAMCL1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed