SCHEMBL24909367

SCHEMBL24909367

Cc1cc(-c2cc(C#N)cc(Br)c2O)ccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.49
ALB P02768 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PTGS2 P35354 2/20 0.36
PTGS1 P23219 1/20 0.36
XDH P47989 6/20 0.34
SLC22A12 Q96S37 6/20 0.34
AR P10275 3/20 0.33
S1PR1 P21453 2/20 0.33
SIRT1 Q96EB6 1/20 0.32
CYP19A1 P11511 1/20 0.32
MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24910063 0.87 TTR (0.53) TTRALBMEN1KMT2AXDH
SCHEMBL24910093 0.84 MEN1 (0.50) TTRALBMEN1KMT2AXDH
SCHEMBL24909899 0.83 MEN1 (0.45) TTRALBMEN1KMT2APTGS2
SCHEMBL24909769 0.82 TTR (0.50) TTRALBMEN1KMT2AXDH
SCHEMBL24910051 0.80 MEN1 (0.45) TTRALBMEN1KMT2APTGS2
SCHEMBL24909826 0.79 TTR (0.62) TTRALBMEN1KMT2APTGS1
SCHEMBL24910002 0.78 MEN1 (0.46) TTRALBMEN1KMT2APTGS2
SCHEMBL24909835 0.77 MEN1 (0.51) TTRALBMEN1KMT2A
SCHEMBL24909767 0.77 TTR (0.51) TTRALBMEN1KMT2APTGS2
SCHEMBL24909706 0.76 TTR (0.58) TTRALBMEN1KMT2AXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885MEN1 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.