SCHEMBL24909892

SCHEMBL24909892

COc1ccc(-c2cc(C#N)cc(Br)c2O)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
TTR P02766 1/20 0.46
ALB P02768 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
RPS6KA3 P51812 1/20 0.43
SCN9A Q15858 1/20 0.42
CYP2A6 P11509 2/20 0.42
ERN1 O75460 4/20 0.41
LRRK2 Q5S007 1/20 0.39
TDO2 P48775 1/20 0.39
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
FYN P06241 2/20 0.38
KCNH2 Q12809 1/20 0.38
PDGFRB P09619 1/20 0.37
PDGFRA P16234 1/20 0.37
OXTR P30559 1/20 0.36
ELANE P08246 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24910064 0.81 RPS6KA3 (0.44) HSD17B1HSD17B2RPS6KA3SCN9ACYP2A6
SCHEMBL24909858 0.81 MEN1 (0.51) MEN1TTRALBKMT2A
SCHEMBL24909737 0.80 MEN1 (0.50) MEN1TTRALBKMT2ACYP2A6
SCHEMBL24909855 0.80 TTR (0.44) MEN1TTRALBKMT2ALRRK2
SCHEMBL24909362 0.80 MEN1 (0.44) MEN1TTRALBKMT2AFYN
SCHEMBL24909373 0.79 MEN1 (0.43) MEN1TTRALBKMT2ARPS6KA3
SCHEMBL24909992 0.79 MEN1 (0.43) MEN1TTRALBKMT2ASCN9A
SCHEMBL24909715 0.77 TTR (0.55) MEN1TTRALBKMT2A
SCHEMBL24909929 0.77 TTR (0.55) MEN1TTRALBKMT2ALRRK2
SCHEMBL17672770 0.77 SCN9A (0.49) HSD17B1HSD17B2RPS6KA3SCN9ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 MEN1 3221/4885TTR 4497/4885ALB 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.