Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 16/20 | 0.49 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30171555 | 1.00 | TTK (0.49) | TTKMAPKAPK5ALDH2AXLPTK6 | |
| SCHEMBL22139112 | 1.00 | TTK (0.49) | TTKMAPKAPK5ALDH2AXLPTK6 | |
| SCHEMBL30172021 | 0.96 | TTK (0.48) | TTKMAPKAPK5ALDH2PTK6 | |
| SCHEMBL24870705 | 0.96 | TTK (0.48) | TTKMAPKAPK5ALDH2PTK6 | |
| SCHEMBL30171640 | 0.91 | TTK (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL22124284 | 0.91 | TTK (0.49) | TTKMAPKAPK5AXL | |
| SCHEMBL22124379 | 0.90 | TTK (0.49) | TTKMAPKAPK5PTK6 | |
| SCHEMBL30171837 | 0.90 | TTK (0.49) | TTKMAPKAPK5PTK6 | |
| SCHEMBL24871004 | 0.90 | MAPKAPK5 (0.45) | TTKMAPKAPK5PTK6 | |
| SCHEMBL30172097 | 0.90 | MAPKAPK5 (0.45) | TTKMAPKAPK5PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |