Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 9/20 | 0.51 |
| ▸ | SYK | P43405 | 5/20 | 0.47 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349717 | 0.93 | TTK (0.47) | TTKSYKPTK6AURKBMAPKAPK5 | |
| SCHEMBL22122923 | 0.93 | PTK6 (0.49) | TTKSYKPTK6AURKBMAPKAPK5 | |
| SCHEMBL30171768 | 0.93 | PTK6 (0.49) | TTKSYKPTK6AURKBMAPKAPK5 | |
| SCHEMBL22122930 | 0.90 | TTK (0.49) | TTKSYKPTK6MAPKAPK5 | |
| SCHEMBL22122881 | 0.86 | TTK (0.50) | TTKPTK6MAPKAPK5 | |
| SCHEMBL22123172 | 0.86 | TTK (0.41) | TTKSYKPTK6PTK2POLB | |
| SCHEMBL30171980 | 0.86 | TTK (0.41) | TTKSYKPTK6PTK2POLB | |
| SCHEMBL24978344 | 0.86 | TTK (0.47) | TTKSYKPTK6AURKBMAPKAPK5 | |
| SCHEMBL25170256 | 0.84 | MAPKAPK5 (0.48) | TTKSYKPTK6AURKBMAPKAPK5 | |
| SCHEMBL30385742 | 0.84 | MAPKAPK5 (0.48) | TTKSYKPTK6AURKBMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |