Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 16/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.43 |
| ▸ | LCK | P06239 | 6/20 | 0.39 |
| ▸ | TTK | P33981 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139162 | 1.00 | PTK6 (0.46) | PTK6AURKBLCKTTK | |
| SCHEMBL22124057 | 1.00 | PTK6 (0.46) | PTK6AURKBLCKTTK | |
| SCHEMBL30177662 | 1.00 | PTK6 (0.46) | PTK6AURKBLCKTTK | |
| Hydrochloric Acid SCHEMBL30171821 | 0.99 | PTK6 (0.46) | PTK6AURKBLCKTTK | |
| SCHEMBL30177870 | 0.96 | PTK6 (0.49) | PTK6AURKBLCKTTK | |
| SCHEMBL22124012 | 0.96 | PTK6 (0.49) | PTK6AURKBLCKTTK | |
| SCHEMBL22125157 | 0.95 | PTK6 (0.46) | PTK6AURKBLCKTTK | |
| SCHEMBL30171865 | 0.95 | PTK6 (0.46) | PTK6AURKBLCKTTK | |
| SCHEMBL22124113 | 0.94 | PTK6 (0.48) | PTK6AURKBLCKTTK | |
| SCHEMBL22139128 | 0.94 | PTK6 (0.48) | PTK6AURKBLCKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |