SCHEMBL249124

SCHEMBL249124

[CH2]CC(C)C([CH2])C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5985870 0.79
SCHEMBL1771907 0.79
SCHEMBL5985475 0.74
SCHEMBL5985167 0.74
SCHEMBL56024 0.72
SCHEMBL5984610 0.72
SCHEMBL5985217 0.72
SCHEMBL56390 0.72
SCHEMBL2000099 0.70
SCHEMBL15301 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357268-A1 PREPARATION AND APPLICATION OF TRICYCLIC PYRIMIDINONE COMPOUND AND ITS COMPOSITION NEUSCO BIOTECH LIMITED (CN) 2023-11-09 US claimed
US-20230271980-A1 PREPARATION AND APPLICATION OF TRICYCLIC PYRIMIDINONE COMPOUND AND ITS COMPOSITION NEUSCO BIOTECH LIMITED (CN) 2023-08-31 US claimed
US-20230212168-A1 ENDOCYCLIC PYRIMIDINONE COMPOUNDS, AND PREPARATION METHODS, COMPOSITIONS AND USE THEREOF NEUSCO BIOTECH LIMITED (CN) 2023-07-06 US claimed
EP-4180436-A1 TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF Neusco Biotech Limited (CN) 2023-05-17 EP claimed
EP-4174070-A1 TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF Neusco Biotech Limited (CN) 2023-05-03 EP claimed
EP-4151638-A1 BRIDGED CYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, COMPOSITION CONTAINING SAME AND USE THEREOF Neusco Biotech Limited (CN) 2023-03-22 EP claimed
CN-113912622-A Tricyclic pyrimidone compounds, preparation method, composition and application thereof 上海纽思克生物科技有限公司 2022-01-11 CN claimed
WO-2022001881-A1 TRICYCLIC PYRIMIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF 上海纽思克生物科技有限公司 2022-01-06 WO claimed
CN-113861220-A Tricyclic pyrimidone compounds, preparation method, composition and application thereof 上海纽思克生物科技有限公司 2021-12-31 CN claimed
US-20240216516-A1 GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF TIGER BIOTHERAPEUTICS INC. 2024-07-04 US disclosed
US-20240217972-A1 GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF TIGER BIOTHERAPEUTICS INC. 2024-07-04 US disclosed
WO-2024137981-A1 NAMPT MODULATORS CYTOKINETICS, INCORPORATED (US) 2024-06-27 WO disclosed
US-20240208909-A1 SUBSTITUTED QUINOLINE DERIVATIVES HAVING SOS1 INHIBITION ACTIVITIES AND USES THEREOF ACCUTAR BIOTECHNOLOGY INC. (US) 2024-06-27 US disclosed
US-12018024-B2 Compounds and compositions for the treatment of cryptosporidiosis NOVARTIS AG (CH) 2024-06-25 US disclosed
US-4668756-A POLYLACTAM BLOCK POLYMERS THE DOW CHEMICAL COMPANY (US) 1987-05-26 US disclosed
US-4604450-A ANIONIC POLYMERIZATION OF LACTAMS; RIM; RING OPENING THE DOW CHEMICAL COMPANY (US) 1986-08-05 US disclosed
EP-0163954-A2 Copolymers of lactams and azetidine-2,4-dione-based prepolymers THE DOW CHEMICAL COMPANY (US) 1985-12-11 EP disclosed
US-4550157-A ANIONIC POLYMERIZATION CATALYST THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
EP-0084408-A1 Bicyclooctane compounds and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-27 EP disclosed
US-4328331-A Novel polyester-amides THE UPJOHN COMPANY (US) 1982-05-04 US disclosed