SCHEMBL2491382

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2491071	0.81	MAPT (0.52)	MAPTALDH1A1GAANAMPTMEN1
	SCHEMBL2488454	0.79	TDP1 (0.55)	TDP1MPIMAPTALDH1A1SMN1; SMN2
	SCHEMBL2486986	0.78	TDP1 (0.54)	TDP1MPIMAPTALDH1A1SMN1; SMN2
	SCHEMBL2490983	0.78	TDP1 (0.45)	TDP1MPIALDH1A1SMN1; SMN2KDM4E
	SCHEMBL2489595	0.78	MPI (0.47)	TDP1MPIMAPTALDH1A1KDM4E
	SCHEMBL2488757	0.78	TDP1 (0.50)	TDP1MPIMAPTALDH1A1HTT
	SCHEMBL2488630	0.77	TDP1 (0.57)	TDP1MPIMAPTALDH1A1POLB
	SCHEMBL2488437	0.77	TDP1 (0.52)	TDP1MPIMAPTALDH1A1SMN1; SMN2
	SCHEMBL2486345	0.76	TDP1 (0.51)	TDP1MPIMAPTALDH1A1SMN1; SMN2
	SCHEMBL6461934	0.75	TDP1 (0.50)	TDP1MPIMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.