Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.79 |
| ▸ | RICTOR | Q6R327 | 14/20 | 0.79 |
| ▸ | RPTOR | Q8N122 | 14/20 | 0.79 |
| ▸ | MAPKAP1 | Q9BPZ7 | 14/20 | 0.79 |
| ▸ | MLST8 | Q9BVC4 | 14/20 | 0.79 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.58 |
| ▸ | PRKDC | P78527 | 2/20 | 0.58 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.57 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494282 | 0.88 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494321 | 0.88 | MTOR (0.83) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL29201811 | 0.87 | MTOR (0.75) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30880103 | 0.87 | MTOR (0.75) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL26570080 | 0.86 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494407 | 0.85 | MTOR (0.82) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494431 | 0.85 | MTOR (0.82) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30382307 | 0.85 | MTOR (0.82) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494263 | 0.85 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494343 | 0.84 | MTOR (0.75) | MTORRICTORRPTORMAPKAP1MLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285926-A1 | SYNTHESIS OF CHIRAL SUBSTITUTED PYRAZOLOPYRIMIDINE COMPOUNDS | Galderma Holding SA (CH) | 2023-01-19 | — | — | WO | disclosed |