SCHEMBL2491636

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19296941	0.88	CYP2B6 (0.63)	CYP2B6KCNH2KCNA5LMNACHRM2
	SCHEMBL2491599	0.88	CYP2B6 (0.63)	CYP2B6KCNH2KCNA5LMNACHRM2
	SCHEMBL2392136	0.86	CYP2B6 (0.59)	CYP2B6CYP11B1CYP11B2KCNH2KCNA5
	SCHEMBL27753492	0.82	CYP2B6 (0.54)	CYP2B6CYP11B1CYP11B2KCNH2KCNA5
	SCHEMBL12199488	0.78	CYP2B6 (0.56)	CYP2B6KCNH2LMNACHRM2CHRM1
	SCHEMBL27544718	0.78	ESR1 (0.52)	CYP2B6KCNH2LMNAMAPTCHRM2
	SCHEMBL2489520	0.78	CYP2B6 (0.56)	CYP2B6KCNH2LMNACHRM2CHRM1
	SCHEMBL9650536	0.77	CYP2B6 (0.46)	CYP2B6CYP11B1CYP11B2KCNH2KCNA5
	SCHEMBL2495637	0.76	ESR1 (0.53)	CYP2B6KCNH2LMNAMAPTCHRM2
	SCHEMBL2490819	0.74	CYP2B6 (0.51)	CYP2B6KCNH2LMNAMAPTCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.