SCHEMBL24916764

SCHEMBL24916764

c1ccc(N2CCc3ccccc3C2C2CCCCC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.71
ESR2 Q92731 2/20 0.71
PRCP P42785 2/20 0.56
HDAC3 O15379 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
NCOR2 Q9Y618 1/20 0.49
KCNH2 Q12809 6/20 0.48
CYP2D6 P10635 6/20 0.45
SIGMAR1 Q99720 2/20 0.44
CHRNA7 P36544 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24157610 0.85 ESR1 (0.51) ESR1ESR2PRCPSIGMAR1CHRNA7
SCHEMBL24917122 0.85 ESR1 (0.54) ESR1ESR2PRCPHDAC3HDAC8
SCHEMBL25163184 0.85 ESR1 (0.54) ESR1ESR2PRCPHDAC3HDAC8
SCHEMBL24916734 0.85 ESR1 (0.54) ESR1ESR2PRCPHDAC3HDAC8
SCHEMBL6722964 0.84 ESR1 (1.00) ESR1ESR2
SCHEMBL6716286 0.81 ESR1 (0.69) ESR1ESR2
SCHEMBL27778413 0.78 PRCP (0.58) ESR1ESR2PRCPHDAC3HDAC8
SCHEMBL8001224 0.78 PRCP (0.58) ESR1ESR2PRCPHDAC3HDAC8
SCHEMBL28926407 0.77 ESR1 (0.46) ESR1ESR2PRCPSIGMAR1CHRNA7
SCHEMBL29972987 0.77 ESR1 (0.46) ESR1ESR2PRCPSIGMAR1CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122940-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS Versitech Limited (CN) 2023-01-25 EP disclosed
CN-115636840-A Binuclear gold (I) compounds for photocatalytic applications 港大科桥有限公司 2023-01-24 CN disclosed