SCHEMBL249175

SCHEMBL249175

C[CH]C1(CC)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5726524 0.88
SCHEMBL892131 0.85
SCHEMBL756797 0.73
SCHEMBL11844840 0.71
SCHEMBL10530709 0.71
SCHEMBL9847365 0.71
SCHEMBL5093847 0.66
SCHEMBL11630889 0.61
SCHEMBL1056660 0.61
SCHEMBL12304972 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11925690-B2 Bifunctional molecules for targeting Rpn11 AMPHISTA THERAPEUTICS LIMITED (GB) 2024-03-12 US disclosed
EP-3063154-B1 CROSS-COUPLING OF UNACTIVATED SECONDARY BORONIC ACIDS UNIV ILLINOIS (US) 2023-08-30 EP disclosed
US-20220313656-A1 NEW CLASS OF ANTIBIOTICS HAVING LOW MIC-VALUES TOWARDS DIFFERENT STRAINS OF BACTERIA Københavns Universitet (DK) 2022-10-06 US disclosed
US-20210283139-A1 BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 AMPHISTA THERAPEUTICS LIMITED (GB) 2021-09-16 US disclosed
US-11005108-B2 Molecularly tunable heterogeneous catalysts by edge functionalization of graphitic carbons MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-05-11 US disclosed
EP-3807263-A1 BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 Amphista Therapeutics Ltd (GB) 2021-04-21 EP disclosed
EP-3807272-A1 BIFUNCTIONAL MOLECULES FOR TARGETING RPN11 Amphista Therapeutics Ltd (GB) 2021-04-21 EP disclosed
CN-112585127-A Bifunctional molecules for targeting Uchl5 安菲斯塔治疗有限责任公司 2021-03-30 CN disclosed
CN-112533918-A Bifunctional molecules for targeting Rpn11 安菲斯塔治疗有限责任公司 2021-03-19 CN disclosed
US-20210009508-A1 Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates NATIONAL SCIENCE FOUNDATION 2021-01-14 US disclosed
EP-1689405-B1 THIORIDAZINE AND DERIVATIVES THEREOF FOR REVERSING ANTI-MICROBIAL DRUG-RESISTANCE NOA SIC APS (DK) 2011-11-09 EP disclosed
US-7741352-B2 KCNQ channel modulating compounds and their pharmaceutical use NEUROSEARCH A/S (DK) 2010-06-22 US disclosed
US-20090292024-A1 SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-11-26 US disclosed
EP-1908466-A1 SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Daiichi Sankyo Company, Limited (JP) 2008-04-09 EP disclosed
US-20070287702-A1 Thioridazine And Derivatives Thereof For Reversing Anti-Microbial Drug-Resistance NOA SIC APS (DK) 2007-12-13 US disclosed
EP-1689405-A1 THIORIDAZINE AND DERIVATIVES THEREOF FOR REVERSING ANTI-MICROBIAL DRUG-RESISTANCE Kobenhavns Universitet (DK) 2006-08-16 EP disclosed
US-20060173058-A1 Kcnq channel modulating compounds and their pharmaceutical use NEUROSEARCH A/S (DK) 2006-08-03 US disclosed
EP-1603858-A2 KCNQ CHANNEL MODULATING COMPOUNDS AND THEIR PHARMACEUTICAL USE NeuroSearch A/S (DK) 2005-12-14 EP disclosed
WO-2005046694-A1 THIORIDAZINE AND DERIVATIVES THEREOF FOR REVERSING ANTI-MICROBIAL DRUG-RESISTANCE Københavns Universitet (DK) 2005-05-26 WO disclosed
WO-2004080377-A2 KCNQ CHANNEL MODULATING COMPOUNDS AND THEIR PHARMACEUTICAL USE NEUROSEARCH A/S (DK) 2004-09-23 WO disclosed