SCHEMBL2491827

SCHEMBL2491827

C=NOC(=O)ON=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27322751 0.81
SCHEMBL9336237 0.77
SCHEMBL26126849 0.74
SCHEMBL28653916 0.74 ELANE (0.39)
SCHEMBL2286989 0.74
SCHEMBL214908 0.72
SCHEMBL27388382 0.67
SCHEMBL8323409 0.65
SCHEMBL28070750 0.65
SCHEMBL18928615 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855490-B2 Method for attaching biological molecules to a glass surface MEDICAL DISCOVERY PARTNERS LLC (US) 2005-02-15 US claimed
JP-2004502837-A 2004-01-29 JP claimed
US-6652970-B1 Stable after transformation 3M INNOVATIVE PROPERTIES COMPANY 2003-11-25 US claimed
US-20030166261-A1 Quality control for cytochemical assays CYTOLOGIX CORPORATION 2003-09-04 US claimed
EP-1301470-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M Innovative Properties Company (US) 2003-04-16 EP claimed
WO-2002004408-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO claimed
WO-2002004548-A1 POLYMER COMPOSITIONS WITH ENERGETICALLY DEGRADABLE CROSSLINKER 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO claimed
US-5276187-A Ketoxime carbonates and process for the synthesis of ketoxime carbonates generally ALLIEDSIGNAL INC. (US) 1994-01-04 US claimed
WO-1993004037-A1 KETOXIME CARBONATES AND PROCESS FOR THEIR SYNTHESIS ALLIED-SIGNAL INC. (US) 1993-03-04 WO claimed
US-20180362583-A1 INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER H LEE MOFFITT CANCER CT & RES (US) 2018-12-20 US disclosed
US-10059740-B2 Integrin interaction inhibitors for the treatment of cancer H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2018-08-28 US disclosed
US-20160257712-A1 INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER H LEE MOFFITT CANCER CT & RES (US) 2016-09-08 US disclosed
US-20150071918-A1 PEPTIDES FOR THE TREATMENT OF CANCER UNIVERSITY OF SOUTH FLORIDA 2015-03-12 US disclosed
EP-2547693-B1 INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER H LEE MOFFITT CANCER CT & RES (US) 2015-03-11 EP disclosed
US-5276187-A Ketoxime carbonates and process for the synthesis of ketoxime carbonates generally ALLIEDSIGNAL INC. (US) 1994-01-04 US disclosed
US-5276187-A Ketoxime carbonates and process for the synthesis of ketoxime carbonates generally ALLIEDSIGNAL INC. (US) 1994-01-04 US disclosed
US-5276187-A Ketoxime carbonates and process for the synthesis of ketoxime carbonates generally ALLIEDSIGNAL INC. (US) 1994-01-04 US disclosed
WO-1993004037-A1 KETOXIME CARBONATES AND PROCESS FOR THEIR SYNTHESIS ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed
WO-1993004037-A1 KETOXIME CARBONATES AND PROCESS FOR THEIR SYNTHESIS ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed
WO-1993004037-A1 KETOXIME CARBONATES AND PROCESS FOR THEIR SYNTHESIS ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed